نوع مقاله : مقاله پژوهشی
نویسندگان
1 گروه تربیت بدنی و علوم ورزشی، واحد بجنورد، دانشگاه آزاد اسلامی، بجنورد، ایران
2 گروه فیزیوتراپی، دانشکده پیراپزشکی، دانشگاه علوم پزشکی مشهد، مشهد، ایران
چکیده
کلیدواژهها
موضوعات
عنوان مقاله [English]
نویسندگان [English]
Background and Aim: Blood flow restriction (BFR) training has been suggested as an effective method to improve muscle hypertrophy and in rehabilitation approach. The aim of the present study was to investigate the effect of resistance training accompanied by BFR on serum levels of sirtuin-1 (SIRT-1), visfatin and nitric oxide (NO) in elite male athletes after anterior cruciate ligament (ACL) surgery.
Materials and Methods: Twenty elite male athletes voluntarily participated in the study and randomly divided into two groups of 1) resistance training- blood flow restriction (RT-BFR), and 2) resistance training (RT) (10 ones in each group). Subjects in both groups participated in 12 weeks of resistance training (at intensity of 30 to 70 percentage of 10 repetition maximum, 2- 4 sets). Whereas, subjects in group of RT-BFR performed resistance training by placing blood pressure cuff in the upper thigh with a pressure of 120-180 mm Hg. Blood samples were collected before and 48 hours after the last training session to measure serum levels of blood factors assessed. Data analysis was done by analysis of covariance (ANCOVA) and paired t test and P<0.05 considered significant.
Results: Twelve weeks of RT-BFR significantly increased serum levels of SIRT-1 (P<0.001(, visfatin (P= 0.02) and NO (P=0.01) in post-test in comparison to the pre-test. Furthermore, between groups analysis showed that RT-BFR increased serum levels of SIRT-1 (P<0.001) and NO (P=0.002) compared to RT group.
Conclusion: Resistance training combined with blood flow restriction versus resistance training alone after ACL reconstruction in elite athletes can increase serum concentration of SIRT-1 and NO.
کلیدواژهها [English]
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